Combined granular lattice dystrophy (Avellino corneal dystrophy)

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Avellino corneal dystrophy.

LABORATORY DATA chromosomal assignment chromosome 5q localization gene, structural-functional anomalies gene analysis-DNA analysis TGFBI (CSD2) (CDGG1) (CSD) (BIGH3) transforming growth factor, beta-induced 68kD, gene chr.5q31 OCULAR DISORDERS corneal defects not including dystrophy isolated ocular defects: corneal dystrophy, isolated defects corneal dystrophy, isolated defect corneal dystrophy...

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Histochemistry of corneal granular dystrophy.

Since the introduction by Jones and Zimmerman (I 959, I 96 I) of a reliable histological scheme for the separate recognition of each of the three major categories of corneal stromal dystrophy, the way has been open for precise characterization of the nature of the lesions in each of these conditions. This has been largely accomplished for the macular and lattice dystrophies, the former having b...

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Individual phenotypic variances in a family with Avellino corneal dystrophy

BACKGROUND Avellino corneal dystrophy (ACD) is an autosomal dominant disorder, characterized by the presence of deposits in the anterior stroma, and results from a specific mutation (R124H) in the transforming growth factor beta-induced gene (TGFBI). This report presents corneal dystrophy of the Bowman layer as a rare phenotypic appearance of ACD and a high intra-familial variability of phenoty...

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Sands of Sahara after LASIK in Avellino Corneal Dystrophy

We report the case of a patient diagnosed with Avellino corneal dystrophy (ACD) who developed diffuse interstitial keratitis following excimer laser insitu keratomileusis (LASIK). ACD is an autosomal dominant corneal dystrophy characterized by multiple asymmetric stromal opacities that impair vision. Accepted treatments for this condition include corneal transplantation and phototherapeutic ker...

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Lattice corneal dystrophy: a source of confusion.

Published descriptions of families with lattice dystrophy of the cornea reveal a much more varied clinical course and a more pleomorphic corneal picture than the rather stereotyped textbook descriptions would suggest. This report describes a family with lattice dystrophy of unusually late onset with retention of useful vision into the 7th decade. Herpes simplex keratitis was misdiagnosed in 5 m...

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ژورنال

عنوان ژورنال: British Journal of Ophthalmology

سال: 1996

ISSN: 0007-1161

DOI: 10.1136/bjo.80.5.489